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. 2016 Jun 1;78(5):889-93.
doi: 10.1292/jvms.15-0502. Epub 2016 Feb 1.

Effect of road transportation on the serum biochemical parameters of cynomolgus monkeys and beagle dogs

Takehiro Ochi  1 , Azusa Yamada, Yuki Naganuma, Noriko Nishina, Hironari Koyama
Affiliations

Effect of road transportation on the serum biochemical parameters of cynomolgus monkeys and beagle dogs

Takehiro Ochi et al. J Vet Med Sci. .

Abstract

To determine the effect of long-distance (approximately 600 km) road transportation on the blood biochemistry of laboratory animals, we investigated the changes in serum biochemical parameters in healthy cynomolgus monkeys and beagle dogs transported by truck from Osaka to Tsukuba, Japan. The concentrations of serum cortisol, total bilirubin and aspartate aminotransferase in monkeys increased during transportation. Serum cortisol and total bilirubin levels in dogs also increased during transportation, but serum triglyceride decreased. Serum parameter values in truck-transported monkeys and dogs returned to baseline levels within two weeks following arrival. Taken together, these results suggest that a two-week acclimation period is the minimum duration required for adaptation following road transportation.

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Figures

Fig. 1.
Fig. 1.
Changes in serum parameters values after transportation in cynomolgus monkeys and beagle dogs. Values are means ± SEM. Statistical significance was analyzed using the paired t-test for two groups. ++P<0.01 and **P<0.01 indicate a significant difference from the value obtained immediately following arrival.
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