Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015 Dec;12(4):283-6.
doi: 10.14245/kjs.2015.12.4.283. Epub 2015 Dec 31.

Plasmacytoma to the Axis Mimicking Metastatic Paraganglioma: Circumferential Reconstruction via Posterior Approach

Affiliations

Plasmacytoma to the Axis Mimicking Metastatic Paraganglioma: Circumferential Reconstruction via Posterior Approach

Young-Seop Park et al. Korean J Spine. 2015 Dec.

Abstract

Plasmacytoma is a malignant plasma cell tumor growing within soft tissue or the axial skeleton. Here, we present the case of a patient with plasmacytoma of the axis vertebra who underwent decompressive surgery with reconstruction via a posterior approach. The patient was referred because of quadriparesis with severe neck pain. Magnetic resonance imaging revealed a relatively demarcated, highly enhanced mass lesion in a destructed axis, with spinal cord compression. Computed tomography revealed a 5.6×4.3 cm adrenal mass at the left retroperitoneal space. We suspected the axis lesion to be a metastatic paraganglioma from the adrenal mass. The patient underwent total excision of the tumor under an operative microscope with occipitocervical fixation. Histopathologically, the tumor was shown to be a plasmacytoma. Following the operation, the patient recovered without significant complications. This was a rare case of plasmacytoma in the axis, mimicking metastatic paraganglioma.

Keywords: Axis; Fusion; Paraganglioma; Plasmacytoma; Posterior surgery.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1. Plain radiograph showing osteolysis of the axis with malaligment. (A) A lateral cervical plain radiograph, (B) An open mouth radiograph.
Fig. 2
Fig. 2. A mass lesion extending along the anterior epidural space with cord compression at preoperative MRI. (A) Contrast-enhanced sagittal MRI, (B) Contrast-enhanced axial MRI, (C) T2 sagittal MRI.
Fig. 3
Fig. 3. An abdominal PET/CT image showing a 5.6×4.3 cm size mass at the left retroperitoneum.
Fig. 4
Fig. 4. Postoperative 12 months later, a CT image showing bony bridge formation through the implanted mesh. (A) Sagittal CT image, (B) Postoperative CT 3D reconstruction image.

Similar articles

Cited by

References

    1. Chak LY, Cox RS, Bostwick DG, Hoppe RT. Solitary plasmacytoma of bone: treatment, progression, and survival. J Clin Oncol. 1987;5:1811–1815. - PubMed
    1. Dimopoulos MA, Hamilos G. Solitary bone plasmacytoma and extramedullary plasmacytoma. Curr Treat Options Oncol. 2002;3:255–259. - PubMed
    1. Dimopoulos MA, Moulopoulos LA, Maniatis A, Alexanian R. Solitary plasmacytoma of bone and asymptomatic multiple myeloma. Blood. 2000;96:2037–2044. - PubMed
    1. Grogan TM, Muller-Hermelink HK, Van CB, Harris NL, Kyle RA. Plasm cell neoplasms. In: Jaffe ES, Harris NL, Stein H, Vardiman JW, editors. World health organization classification of tumours. Pathology and genetics of tumours of haematopoietic and lymphoid tissues. Lyon: IARC Press; 2001. pp. 142–156.
    1. Ghogawala Z, Mansfield FL, Borges LF. Spinal radiation before surgical decompression adversely affects outcomes of surgery for symptomatic metastatic spinal cord compression. Spine (Phila Pa 1976) 2001;26:818–824. - PubMed

LinkOut - more resources