Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015 Aug;4(2):100-7.
doi: 10.15420/aer.2015.04.02.100.

Anticoagulation in Atrial Fibrillation - Current Concepts

Demosthenes G Katritsis  1 , Bernard J Gersh  2 , A John Camm  3
Affiliations

Anticoagulation in Atrial Fibrillation - Current Concepts

Demosthenes G Katritsis et al. Arrhythm Electrophysiol Rev. 2015 Aug.

Abstract

This article presents the current status of the use of anticoagulation for the treatment of AF, particularly with the use of non-vitamin K-dependent anticoagulants. Comparisons between these agents and warfarin are made and methods for assessment of anticoagulant activity and reversal are discussed.

Keywords: Atrial fibrillation; anticoagulants; guidelines; thromboprophylaxis.

PubMed Disclaimer

Figures

Figure 1:
Figure 1:. Choice of Anticoagulant for Atrial Fibrillation
Figure 2:
Figure 2:. Coagulation Cascade
Figure 3:
Figure 3:. Management of Bleeding in Patients Taking Non-vitamin K Oral Anticoagulants
See this image and copyright information in PMC

References

    1. January CT, Wann LS, Alpert JS 2014 AHA/ACC/ HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/ American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society. J Am Coll Cardiol. 2014. :64:e1–76. - PubMed
    1. Wolf PA, Abbott RD, Kannel WB. Atrial fibrillation as an independent risk factor for stroke: The Framingham study. Stroke. 1991;22:983–8. - PubMed
    1. Healey JS, Connolly SJ, Gold MR et al. Subclinical atrial fibrillation and the risk of stroke. N Engl J Med. 2012;366:120–9. - PubMed
    1. Gladstone DJ, Spring M, Dorian P et al. Atrial fibrillation in patients with cryptogenic stroke. N Engl J Med. 2014;370:2467–77. - PubMed
    1. Sanna T, Diener H-C, Passman RS et al. Cryptogenic stroke and underlying atrial fibrillation. N Engl J Med. 2014;370:2478–86. - PubMed