Acromegaly Presenting as Erectile Dysfunction: Case Reports and Review of the Literature
- PMID: 26839523
- PMCID: PMC4735672
Acromegaly Presenting as Erectile Dysfunction: Case Reports and Review of the Literature
Abstract
Erectile dysfunction (ED) is a common yet complex condition. The authors report two cases of acromegaly presenting with ED and hypogonadotropic hypogonadism. Surgical cure of the acromegaly was associated with either an improvement or resolution of hypogonadotropic hypogonadism-associated ED. Active acromegaly should be considered in the differential diagnosis of ED presenting with supporting clinical features, particularly hypogonadotropic hypogonadism.
Keywords: Acromegaly; Endocrine dysfunction; Endocrinology; Erectile dysfunction; Growth hormone.
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References
-
- Lewis RW, Fugl-Meyer KS, Corona G, et al. Definitions/epidemiology/risk factors for sexual dysfunction. J Sex Med. 2010;7(4 Pt 2):1598–1607. - PubMed
-
- Hackett G, Kell P, Ralph D, et al. British Society for Sexual Medicine, authors. British Society for Sexual Medicine guidelines on the management of erectile dysfunction. J Sex Med. 2008;5:1841–1865. - PubMed
-
- Hatzimouratidis K, Amar E, Eardley I, et al. European Association of Urology, authors. Guidelines on male sexual dysfunction: erectile dysfunction and premature ejaculation. Eur Urol. 2010;57:804–814. - PubMed
-
- Katznelson L, Kleinberg D, Vance ML, et al. Hypogonadism in patients with acromegaly: data from the multi-centre acromegaly registry pilot study. Clin Endocrinol. 2001;54:183–188. - PubMed
-
- Galdiero M, Pivonello R, Grasso LF, et al. Growth hormone, prolactin, and sexuality. J Endocrinol Invest. 2012;35:782–794. - PubMed
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