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Review
. 2015;17(4):250-1.

Sorafenib-induced Scrotal Eczema

Selahattin Çalışkan  1
Affiliations
Review

Sorafenib-induced Scrotal Eczema

Selahattin Çalışkan. Rev Urol. 2015.

Abstract

Sorafenib is an orally active, small-molecule multikinase inhibitor that blocks tumor cell proliferation and angiogenesis. Studies have shown that it is a highly potent, selective inhibitor of vascular endothelial growth factor receptors 2 and 3, platelet-derived growth factor-β, RAF, FLT-3, and c-Kit. This drug was recently approved for the treatment of metastatic renal cell carcinoma and hepatocellular carcinoma. We report a case of a patient treated with sorafenib for metastatic renal cell carcinoma who developed scrotal eczema.

Keywords: Hand-foot skin reaction; Scrotal eczema; Sorafenib.

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Figures

Figure 1
Figure 1
Scrotal eczema caused by sorafenib treatment.
Figure 2
Figure 2
Sorafenib-induced scrotal eczema after topical steroid treatment.
See this image and copyright information in PMC

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