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Review
. 2016 Feb 3:11:18.
doi: 10.1186/s13000-016-0469-3.

Massive ovarian oedema: a misleading clinical entity

Nikolaos Machairiotis  1 , Aikaterini Stylianaki  2 , Paraskevi Kouroutou  3 , Polixeni Sarli  1 , Nikolaos Konstantinos Alexiou  1 , Elias Efthymiou  1 , Athanasios Maras  1 , Nikolaos Georgios Alexiou  3 , Spyridon Evaggelos Nikolaou  3 , Nikolaos Courcoutsakis  4 , Eleni Papakonstantinou  5 , Paul Zarogoulidis  6 , Nikolaos Barbetakis  7 , Dimitrios Paliouras  7 , Apostolos Gogakos  7 , Christodoulos Machairiotis  1
Affiliations
Review

Massive ovarian oedema: a misleading clinical entity

Nikolaos Machairiotis et al. Diagn Pathol. .

Abstract

Background: Massive ovarian oedema is a rare non-neoplastic clinicopathologic entity has a higher incidence in women during their second and third life decade. The oedema can be presented in one or both ovaries as a result of partial intermittent torsion of the ovarian pedicle that interferes to the venal and lymphatic drainage of the ovary.

Case presentation: We present a clinical case of a 16 year old with massive ovarian oedema and we performed a review of the literature. The pathophysiology of this entity is very complex. We tried to perform a complete review of the literature and focus on the complexity of this entity as far as its pathophysiological backround is concerned and as far as its clinical presentation is concerned.

Conclusions: In conclusion, massive ovarian oedema is a rare, multi disease mimicking clinical entity, with an acute or progressive clinical presentation. It has also to be a part of our differential diagnosis in cases of acute abdominal pain and we have to try to treat her conservatively, in order to preserve fertility.

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Figures

Fig. 1
Fig. 1
a and b: axial, unenhanced CT images of the pelvis demonstrate a voluminous mass [arrows] which displace the adjacent viscera [small intestine and uterus (star)]
Fig. 2
Fig. 2
a incision of the ovary and triple torsion of the ovarian pedicle b anti-rotation of the pedicle – exclusion of possible ischemia or necrosis c (i)-(ii) excision of the mass
Fig. 3
Fig. 3
Red arrow; cystic lesions of the ovary, black arrow; stromal oedema
Fig. 4
Fig. 4
a cluster of lutein cells in the ovarian stroma b oedematous, fibroblastic stroma surrounding follicles and cluster of lutein cells on the left c οedematous, fibroblastic stroma surrounding follicles
See this image and copyright information in PMC

References

    1. Kalstone CE, Jaffe RB, Abell MR. Massive edema of the ovary simulating fibroma. Obstet Gynecol. 1969;34(4):564–71. - PubMed
    1. Roth LM, Deaton RL, Sternberg WH. Massive ovarian edema. A clinicopathologic study of five cases including ultrastructural observations and review of the literature. Am J Surg Pathol. 1979;3(1):11–21. doi: 10.1097/00000478-197902000-00002. - DOI - PubMed
    1. Nogales FF, Martin-Sances L, Mendoza-Garcia E, Salamanca A, Gonzalez-Nunez MA, Pardo Mindan FJ. Massive ovarian oedema. Histopathology. 1996;28(3):229–34. doi: 10.1046/j.1365-2559.1996.d01-420.x. - DOI - PubMed
    1. Eden JA. Massive ovarian oedema. Br J Obstet Gynaecol. 1994;101(5):456–8. doi: 10.1111/j.1471-0528.1994.tb11928.x. - DOI - PubMed
    1. Roth LM. Massive ovarian edema with stromal luteinization: a newly recognized virilizing syndrome apparently related to partial torsion of the mesovarium. Am J Clin Pathol. 1971;55(6):757–60. - PubMed