Population-Based Estimates of Decreases in Quality-Adjusted Life Expectancy Associated with Unhealthy Body Mass Index
- PMID: 26843684
- PMCID: PMC4716486
- DOI: 10.1177/003335491613100125
Population-Based Estimates of Decreases in Quality-Adjusted Life Expectancy Associated with Unhealthy Body Mass Index
Abstract
Objective: Being classified as outside the normal range for body mass index (BMI) has been associated with increased risk for chronic health conditions, poor health-related quality of life (HRQOL), and premature death. To assess the impact of BMI on HRQOL and mortality, we compared quality-adjusted life expectancy (QALE) by BMI levels.
Methods: We obtained HRQOL data from the 1993-2010 Behavioral Risk Factor Surveillance System and life table estimates from the National Center for Health Statistics national mortality files to estimate QALE among U.S. adults by BMI categories: underweight (BMI <18.5 kg/m(2)), normal weight (BMI 18.5-24.9 kg/m(2)), overweight (BMI 25.0-29.9 kg/m(2)), obese (BMI 30.0-34.9 kg/m(2)), and severely obese (BMI ≥35.0 kg/m(2)).
Results: In 2010 in the United States, the highest estimated QALE for adults at 18 years of age was 54.1 years for individuals classified as normal weight. The two lowest QALE estimates were for those classified as either underweight (48.9 years) or severely obese (48.2 years). For individuals who were overweight or obese, the QALE estimates fell between those classified as either normal weight (54.1 years) or severely obese (48.2 years). The difference in QALE between adults classified as normal weight and those classified as either overweight or obese was significantly higher among women than among men, irrespective of race/ethnicity.
Conclusions: Using population-based data, we found significant differences in QALE loss by BMI category. These findings are valuable for setting national and state targets to reduce health risks associated with severe obesity, and could be used for cost-effectiveness evaluations of weight-reduction interventions.
Figures



Similar articles
-
Excess weight and life expectancy after acute myocardial infarction: The obesity paradox reexamined.Am Heart J. 2016 Feb;172:173-81. doi: 10.1016/j.ahj.2015.10.024. Epub 2015 Dec 1. Am Heart J. 2016. PMID: 26856230 Free PMC article.
-
Depression and anxiety among US adults: associations with body mass index.Int J Obes (Lond). 2009 Feb;33(2):257-66. doi: 10.1038/ijo.2008.268. Epub 2009 Jan 6. Int J Obes (Lond). 2009. PMID: 19125163
-
[Body mass index and cancer incidence:a prospective cohort study in northern China].Zhonghua Liu Xing Bing Xue Za Zhi. 2014 Mar;35(3):231-6. Zhonghua Liu Xing Bing Xue Za Zhi. 2014. PMID: 24831616 Chinese.
-
[Overweight, obesity and life expectancy: do people with a high BMI live longer?].Ned Tijdschr Geneeskd. 2016;160:D859. Ned Tijdschr Geneeskd. 2016. PMID: 27966405 Review. Dutch.
-
Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants.Lancet. 2016 Apr 2;387(10026):1377-1396. doi: 10.1016/S0140-6736(16)30054-X. Lancet. 2016. PMID: 27115820 Free PMC article. Review.
Cited by
-
Development and validation of electronic health record-based, machine learning algorithms to predict quality of life among family practice patients.Sci Rep. 2024 Dec 3;14(1):30077. doi: 10.1038/s41598-024-80064-3. Sci Rep. 2024. PMID: 39627388 Free PMC article.
-
Effect of Food Predictability on Life Span in Male Mice.J Gerontol A Biol Sci Med Sci. 2019 Jul 12;74(8):1158-1161. doi: 10.1093/gerona/gly231. J Gerontol A Biol Sci Med Sci. 2019. PMID: 30289438 Free PMC article.
-
The Incomplete Medicalization of Obesity: Physician Office Visits, Diagnoses, and Treatments, 1996-2014.Public Health Rep. 2019 Mar/Apr;134(2):141-149. doi: 10.1177/0033354918813102. Epub 2019 Feb 22. Public Health Rep. 2019. PMID: 30794761 Free PMC article.
-
Changes in quality-adjusted life expectancy in Belgium, 2013 and 2018.Arch Public Health. 2022 Dec 17;80(1):254. doi: 10.1186/s13690-022-01011-0. Arch Public Health. 2022. PMID: 36527095 Free PMC article.
-
Understanding limitations in sport 1 year after an Achilles tendon rupture: a multicentre analysis of 285 patients.Knee Surg Sports Traumatol Arthrosc. 2020 Jan;28(1):233-244. doi: 10.1007/s00167-019-05586-0. Epub 2019 Jun 27. Knee Surg Sports Traumatol Arthrosc. 2020. PMID: 31250056
References
-
- Department of Health and Human Services (US) Rockville (MD): Office of the Surgeon General (US); 2001. The Surgeon General's call to action to prevent and decrease overweight and obesity. - PubMed
-
- Must A, Spadano J, Coakley EH, Field AE, Colditz G, Dietz WH. The disease burden associated with overweight and obesity. JAMA. 1999;282:1523–9. - PubMed
-
- Jia H, Lubetkin EI. The impact of obesity on health-related quality-of-life in the general adult US population. J Public Health (Oxf) 2005;27:156–64. - PubMed
-
- Backholer K, Wong E, Freak-Poli R, Walls HL, Peeters A. Increasing body weight and risk of limitations in activities of daily living: a systematic review and meta-analysis. Obes Rev. 2012;13:456–68. - PubMed
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical