Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2015 Dec;64(12):794-800.

PURLs: Should you bypass anticoagulant "bridging" before and after surgery?

Affiliations
Comment

PURLs: Should you bypass anticoagulant "bridging" before and after surgery?

Jennie B Jarrett et al. J Fam Pract. 2015 Dec.

Abstract

Skipping perioperative use of LMWH in low- and moderate-risk patients on warfarin for atrial fibrillation doesn’t increase their risk of stroke or bleeding.

PubMed Disclaimer

Comment on

  • Perioperative Bridging Anticoagulation in Patients with Atrial Fibrillation.
    Douketis JD, Spyropoulos AC, Kaatz S, Becker RC, Caprini JA, Dunn AS, Garcia DA, Jacobson A, Jaffer AK, Kong DF, Schulman S, Turpie AG, Hasselblad V, Ortel TL; BRIDGE Investigators. Douketis JD, et al. N Engl J Med. 2015 Aug 27;373(9):823-33. doi: 10.1056/NEJMoa1501035. Epub 2015 Jun 22. N Engl J Med. 2015. PMID: 26095867 Free PMC article. Clinical Trial.

References

    1. Douketis JD, Spyropoulos AC, Kaatz S, et al. Perioperative bridging anticoagulation in patients with atrial fibrillation. N Engl J Med. 2015;373:823–833. - PMC - PubMed
    1. Guyatt GH, Akl EA, Crowther M, et al; American College of Chest Physicians Antithrombotic Therapy and Prevention of Thrombosis Panel. Executive summary: Antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest. 2012;141:7S–47S. - PMC - PubMed
    1. Clark NP, Witt DM, Davies LE, et al. Bleeding, recurrent venous thromboembolism and mortality risks during warfarin interruption for invasive procedures. JAMA Intern Med. 2015;175:1163–1168. - PubMed
    1. Lip GY, Lane DA. Stroke prevention in atrial fibrillation; a systematic review. JAMA. 2015;313:1950–1962. - PubMed
    1. Douketis JD, Spyropoulos AC, Spencer FA, et al; American College of Chest Physicians. Perioperative management of antithrombotic therapy: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest. 2012;141:e326S–e350S. - PMC - PubMed

Publication types

MeSH terms

Substances