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Review
. 2016 Feb 4:10:31.
doi: 10.1186/s13256-015-0778-2.

Bilateral orbital myeloid sarcoma preceding acute myeloid leukemia in an adult: a case report and review of the literature

Jesus Vera-Aguilera  1 , Osama Mukarram  2 , Prathibha Nutalapati  3 , Mary Mok  4 , Anushi Bulumulle  5 , Carlos Vera-Aguilera  6
Affiliations
Review

Bilateral orbital myeloid sarcoma preceding acute myeloid leukemia in an adult: a case report and review of the literature

Jesus Vera-Aguilera et al. J Med Case Rep. .

Abstract

Background: Acute myeloid leukemia is typically a disease of the older population and presents mostly in the fifth decade of life. Myeloid sarcoma is a rare initial presentation of acute myeloid leukemia. Previously it has only been documented in children and younger patients.

Case presentation: We present an unusual case of retro-orbital myeloid sarcoma as an initial presentation of acute myeloid leukemia in a 43-year-old Caucasian man, with rearrangement of chromosome 11q23 involving the MLL gene.

Conclusions: We present an unusual case of retro-orbital myeloid sarcoma as an initial presentation of acute myeloid leukemia in a 43-year-old man, with rearrangement of chromosome 11q23 involving the MLL gene.

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Figures

Fig. 1
Fig. 1
Computed tomography scan of the head showing broad-based multiple bilateral retro-orbital masses along the medial side of the lateral rectus muscle, the largest one measuring 10 mm
Fig. 2
Fig. 2
Computed tomography scan of the head showing increase in size of the orbital masses, measuring 3.7 cm on the left and 2.7 cm on the right, causing a mass effect on the optic nerves
See this image and copyright information in PMC

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