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Editorial
. 2016 Feb 5;118(3):368-70.
doi: 10.1161/CIRCRESAHA.116.308139.

Recounting Cardiac Cellular Composition

Affiliations
Editorial

Recounting Cardiac Cellular Composition

Pingzhu Zhou et al. Circ Res. .
No abstract available

Keywords: Editorials; endothelial cell; fibroblasts; myocardium.

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Figures

Figure
Figure. Cellular composition of the mammalian heart
Summary of studies that have measured the proportion of cardiomyocytes (CMs), endothelial cells (ECs), and fibroblasts (FBs) in the heart, using either stereology or flow cytometry. To allow comparison between studies, results are expressed as relative proportions of cells, with CMs assigned a value of one. Where numbers of CM nuclei were measured, cell number was not corrected for multinucleation. Additional assumptions used are noted by superscript letters: A, CM volume is 25 times that of ECs or fibroblasts; B, cells not stained by EC or CM antibodies were fibroblasts. LV, left ventricle. V, ventricles. H, whole heart. pap, papillary muscle. *, fraction of CMs not measured and based on stereology study in same reference.

Comment on

  • Revisiting Cardiac Cellular Composition.
    Pinto AR, Ilinykh A, Ivey MJ, Kuwabara JT, D'Antoni ML, Debuque R, Chandran A, Wang L, Arora K, Rosenthal NA, Tallquist MD. Pinto AR, et al. Circ Res. 2016 Feb 5;118(3):400-9. doi: 10.1161/CIRCRESAHA.115.307778. Epub 2015 Dec 3. Circ Res. 2016. PMID: 26635390 Free PMC article.

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