Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016:1409:135-42.
doi: 10.1007/978-1-4939-3515-4_12.

Visualization of Anticancer Salmonella typhimurium Engineered for Remote Control of Therapeutic Proteins

Vu H Nguyen  1 , Jung-Joon Min  2
Affiliations

Visualization of Anticancer Salmonella typhimurium Engineered for Remote Control of Therapeutic Proteins

Vu H Nguyen et al. Methods Mol Biol. 2016.

Abstract

Tumor-targeting bacteria are studied for their ability to carry therapeutic molecules to tumors or, when designed as imaging probes, to visualize the infection pathway. The present protocol describes a method to achieve remote control of therapeutic gene expression in bacteria which are also engineered to visualize the therapeutic process. This strategy may increase the safety of bacteria used to deliver therapeutic genes to tumors in vivo.

Keywords: Bacteria; Cancer; Cytolysin A; Imaging; pBAD.

PubMed Disclaimer

Publication types

LinkOut - more resources