Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016 Jun;50(6):797-808.
doi: 10.1016/j.amepre.2015.11.003. Epub 2016 Feb 1.

Increasing Coverage of Appropriate Vaccinations: A Community Guide Systematic Economic Review

Verughese Jacob  1 , Sajal K Chattopadhyay  2 , David P Hopkins  2 , Jennifer Murphy Morgan  2 , Adesola A Pitan  2 , John M Clymer  3 ; Community Preventive Services Task Force
Affiliations

Increasing Coverage of Appropriate Vaccinations: A Community Guide Systematic Economic Review

Verughese Jacob et al. Am J Prev Med. 2016 Jun.

Abstract

Context: Population-level coverage for immunization against many vaccine-preventable diseases remains below optimal rates in the U.S. The Community Preventive Services Task Force recently recommended several interventions to increase vaccination coverage based on systematic reviews of the evaluation literature. The present study provides the economic results from those reviews.

Evidence acquisition: A systematic review was conducted (search period, January 1980 through February 2012) to identify economic evaluations of 12 interventions recommended by the Task Force. Evidence was drawn from included studies; estimates were constructed for the population reach of each strategy, cost of implementation, and cost per additional vaccinated person because of the intervention. Analyses were conducted in 2014.

Evidence synthesis: Reminder systems, whether for clients or providers, were among the lowest-cost strategies to implement and the most cost effective in terms of additional people vaccinated. Strategies involving home visits and combination strategies in community settings were both costly and less cost effective. Strategies based in settings such as schools and MCOs that reached the target population achieved additional vaccinations in the middle range of cost effectiveness.

Conclusions: The interventions recommended by the Task Force differed in reach, cost, and cost effectiveness. This systematic review presents the economic information for 12 effective strategies to increase vaccination coverage that can guide implementers in their choice of interventions to fit their local needs, available resources, and budget.

PubMed Disclaimer

Figures

Chart 1
Chart 1
Chart 2
Chart 2
Chart 3
Chart 3
Figure 1
Figure 1
Search process.
See this image and copyright information in PMC

References

Appendix References

    1. Bond LM, Nolan TM, Lester RA. Home vaccination for children behind in their immunisation schedule: a randomised controlled trial. Med J Aust. 1998;168(10):487–490. - PubMed
    1. Jefferson N, Sleight G, Macfarlane A. Immunisation of children by a nurse without a doctor present. BMJ Clin Res. 1987;294(6569):423. http://dx.doi.org/10.1136/bmj.294.6569.423. - DOI - PMC - PubMed
    1. Jones AE. Domiciliary immunisation for preschool child defaulters. BMJ Clin Res. 1984;289(6456):1429. http://dx.doi.org/10.1136/bmj.289.6456.1429. - DOI - PMC - PubMed
    1. LeBaron CW, Starnes DM, Rask KJ. The impact of reminder-recall interventions on low vaccination coverage in an inner-city population. Arch Pediatr Adolesc Med. 2004;158(3):255–261. http://dx.doi.org/10.1001/archpedi.158.3.255. - DOI - PubMed
    1. Lemstra M, Rajakumar D, Thompson A, Moraros J. The effectiveness of telephone reminders and home visits to improve measles, mumps and rubella immunization coverage rates in children. Pediatr Child Health. 2011;16(1):e1. - PMC - PubMed

References

    1. Roush SW, Murphy TV, Vaccine-Preventable Disease Table Working Group Historical comparisons of morbidity and mortality for vaccine-preventable diseases in the United States. JAMA. 2007;298(18):2155–2163. http://dx.doi.org/10.1001/jama.298.18.2155. - DOI - PubMed
    1. CDC. Ten great public health achievements–United States, 1900–1999. MMWR Morb Mortal Wkly Rep. 1999;48(12):241. - PubMed
    1. Advisory Committee on Immunization Practices (ACIP) Recommendations and Immunization Schedules. www.cdc.gov/vaccines/acip/recs/index.html. Accessed july 25, 2015. - PubMed
    1. Zhou F, Shefer A, Wenger J, et al. Economic evaluation of the routine childhood immunization program in the United States, 2009. Pediatrics. 2014;133(4):577–585. http://dx.doi.org/10.1542/peds.2013-0698. - DOI - PubMed
    1. McLaughlin JM, McGinnis JJ, Tan L, Mercatante A, Fortuna J. Estimated human and economic burden of four major adult vaccine-preventable diseases in the United States, 2013. J Prim Prev. 2015;36(4):259–273. http://dx.doi.org/10.1007/s10935-015-0394-3. - DOI - PMC - PubMed

Publication types