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Comment
. 2016 Feb 4;18(2):164-5.
doi: 10.1016/j.stem.2016.01.014.

Naive versus Primed: It's Now Three-Dimensional

Zong Wei  1 , Wange Lu  2
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Free article
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Naive versus Primed: It's Now Three-Dimensional

Zong Wei et al. Cell Stem Cell. .
Free article

Abstract

We are only beginning to understand the higher-order chromatin structure of pluripotent stem cells and its relevance to cell fate. Three recent studies used different approaches to reconstruct the 3D chromatin landscape of naive and primed pluripotent cells, unveiling common features as well as differences between these two states.

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  • 3D Chromosome Regulatory Landscape of Human Pluripotent Cells.
    Ji X, Dadon DB, Powell BE, Fan ZP, Borges-Rivera D, Shachar S, Weintraub AS, Hnisz D, Pegoraro G, Lee TI, Misteli T, Jaenisch R, Young RA. Ji X, et al. Cell Stem Cell. 2016 Feb 4;18(2):262-75. doi: 10.1016/j.stem.2015.11.007. Epub 2015 Dec 10. Cell Stem Cell. 2016. PMID: 26686465 Free PMC article.

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