Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2016 Feb;44(2):106-12.
doi: 10.1016/j.gyobfe.2016.01.001. Epub 2016 Feb 3.

[Is endometriosis a precancerous lesion? Perspectives and clinical implications]

[Article in French]
G Chene  1 , J Caloone  2 , S Moret  2 , K Le Bail-Carval  2 , P Chabert  2 , E Beaufils  2 , G Mellier  2 , G Lamblin  2
Affiliations
Review

[Is endometriosis a precancerous lesion? Perspectives and clinical implications]

[Article in French]
G Chene et al. Gynecol Obstet Fertil. 2016 Feb.

Abstract

Epidemiological studies have shown a relationship between endometriosis and clear cell/endometrioid ovarian cancers (named "Endometriosis Associated Ovarian Cancer" or EAOC). The recent discovery of signaling pathways (especially the SWI/SNF and PI3K/AKT/mTOR pathways) that linked endometriosis and EAOC could lead to the development of specific biomarkers as ARID1A to screen benign to premalignant endometriosis and to new targeted treatment. Moreover, the better understanding of the pathogenesis of the epithelial ovarian cancer arising from the Fallopian tube could allow new early prevention strategies that will be described in this review.

Keywords: ARID1A; Cancer ovarien endométrioïde; Cancer ovarien à cellules claires; Clear cell ovarian carcinoma; Endometrioid ovarian carcinoma; Endometriosis; Endométriose; Fallopian tube; Trompe de Fallope.

PubMed Disclaimer

LinkOut - more resources