Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016 Mar 8;86(10):898-904.
doi: 10.1212/WNL.0000000000002443. Epub 2016 Feb 5.

Integrated systems of stroke care and reduction in 30-day mortality: A retrospective analysis

Affiliations

Integrated systems of stroke care and reduction in 30-day mortality: A retrospective analysis

Aravind Ganesh et al. Neurology. .

Abstract

Objective: To evaluate the association between the presence of integrated systems of stroke care and stroke case-fatality across Canada.

Methods: We used the Canadian Institute of Health Information's Discharge Abstract Database to retrospectively identify a cohort of stroke/TIA patients admitted to all acute care hospitals, excluding the province of Quebec, in 11 fiscal years from 2003/2004 to 2013/2014. We used a modified Poisson regression model to compute the adjusted incidence rate ratio (aIRR) of 30-day in-hospital mortality across time for provinces with stroke systems compared to those without, controlling for age, sex, stroke type, comorbidities, and discharge year. We conducted surveys of stroke care resources in Canadian hospitals in 2009 and 2013, and compared resources in provinces with integrated systems to those without.

Results: A total of 319,972 patients were hospitalized for stroke/TIA. The crude 30-day mortality rate decreased from 15.8% in 2003/2004 to 12.7% in 2012/2013 in provinces with stroke systems, while remaining 14.5% in provinces without such systems. Starting with the fiscal year 2009/2010, there was a clear reduction in relative mortality in provinces with stroke systems vs those without, sustained at aIRR of 0.85 (95% confidence interval 0.79-0.92) in the 2011/2012, 2012/2013, and 2013/2014 fiscal years. The surveys indicated that facilities in provinces with such systems were more likely to care for patients on a stroke unit, and have timely access to a stroke prevention clinic and telestroke services.

Conclusion: In this retrospective study, the implementation of integrated systems of stroke care was associated with a population-wide reduction in mortality after stroke.

PubMed Disclaimer

Figures

Figure
Figure. Incidence rate ratios (IRRs) of 30-day in-hospital mortality for provinces with and without integrated stroke systems
(A) Unadjusted and (B) adjusted IRRs of 30-day in-hospital mortality for provinces with integrated systems of stroke care vs those without such systems.

Comment in

References

    1. Lindsay P, Bayley M, McDonald A, Graham I, Warner G, Phillips S. Toward a more effective approach to stroke: Canadian Best Practice Recommendations for Stroke Care. Can Med Assoc J 2008;178:1418–1425. - PMC - PubMed
    1. Alberts M, Latchaw R, Selman W, et al. Recommendations for comprehensive stroke centers: a consensus statement from the Brain Attack Coalition. Stroke 2005;36:1597–1616. - PubMed
    1. Schwamm L, Pancioli A, Acker JR, et al. Recommendations for the establishment of stroke systems of care: recommendations from the American Stroke Association's Task Force on the Development of Stroke Systems. Stroke 2005;36:690–703. - PubMed
    1. Lewis S. A system in name only: access, variation, and reform in Canada's provinces. N Engl Journal Med 2015;372:497–500. - PubMed
    1. Mamdani M, Tu J. Appendix 5: Emergency/Acute Stroke Task Group Economic Decision Analysis Model. Toronto: Ontario Ministry of Health and Long-Term Care; 2000.

Publication types