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. 2017 Feb;41(1):19-25.
doi: 10.1177/0309364616628341. Epub 2016 Jul 9.

The impact of gender, level of amputation and diabetes on prosthetic fit rates following major lower extremity amputation

Affiliations

The impact of gender, level of amputation and diabetes on prosthetic fit rates following major lower extremity amputation

Fiona Davie-Smith et al. Prosthet Orthot Int. 2017 Feb.

Abstract

Background: Diabetes mellitus is a leading cause of major lower extremity amputation.

Objective: To examine the influence of gender, level of amputation and diabetes mellitus status on being fit with a prosthetic limb following lower extremity amputation for peripheral arterial disease.

Study design: Retrospective analysis of the Scottish Physiotherapy Amputee Research Group dataset.

Results: Within the cohort with peripheral arterial disease ( n = 1735), 64% were men ( n = 1112) and 48% ( n = 834) had diabetes mellitus. Those with diabetes mellitus were younger than those without: mean 67.5 and 71.1 years, respectively ( p < 0.001). Trans-tibial amputation:trans-femoral amputation ratio was 2.33 in those with diabetes mellitus, and 0.93 in those without. A total of 41% of those with diabetes mellitus were successfully fit with a prosthetic limb compared to 38% of those without diabetes mellitus. Male gender positively predicted fitting with a prosthetic limb at both trans-tibial amputation ( p = 0.001) and trans-femoral amputation ( p = 0.001) levels. Bilateral amputations and increasing age were negative predictors of fitting with a prosthetic limb ( p < 0.001). Diabetes mellitus negatively predicted fitting with a prosthetic limb at trans-femoral amputation level ( p < 0.001). Mortality was 17% for the cohort, 22% when the amputation was at trans-femoral amputation level.

Conclusion: Of those with lower extremity amputation as a result of peripheral arterial disease, those with diabetes mellitus were younger, and more had trans-tibial amputation. Although both age and amputation level are good predictors of fitting with a prosthetic limb, successful limb fit rates were no better than those without diabetes mellitus. Clinical relevance This is of clinical relevance to those who are involved in the decision-making process of prosthetic fitting following major amputation for dysvascular and diabetes aetiologies.

Keywords: Diabetes; prosthetics; rehabilitation.

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Conflict of interest statement

The author(s) declared no potential conflicts of interest with respect to the research, authorship and/or publication of this article.

References

    1. Papazafiropoulou A, Tentolouris N, Soldatos R-P, et al. Mortality in diabetic and nondiabetic patients after amputations performed from 1996 to 2005 in a tertiary hospital population: a 3-year follow-up study. J Diabetes Complications 2009; 23(1): 7–11. - PubMed
    1. The Amputee Statistical Database for the United Kingdom 2006/07 Information Services Division, NHS Scotland on behalf of National Amputee Statistical Database (NASDAB) 2009.
    1. Kennon B, Leese GP, Cochrane L, et al. Reduced incidence of lower-extremity amputations in people with diabetes in Scotland: a nationwide study. Diabetes Care 2012; 35(12): 2588–2590. - PMC - PubMed
    1. Holman N, Young RJ, Jeffcoate WJ. Variation in the recorded incidence of amputation of the lower limb in England. Diabetologia 2012; 55(7): 1919–1925. - PubMed
    1. Peters EJ, Childs MR, Wunderlich RP, et al. Functional status of persons with diabetes-related lower-extremity amputations. Diabetes Care 2001; 24(10): 1799–1804. - PubMed