Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2016 Apr:101:57-64.
doi: 10.1016/j.resuscitation.2016.01.012. Epub 2016 Feb 2.

Design and implementation of the Resuscitation Outcomes Consortium Pragmatic Airway Resuscitation Trial (PART)

Henry E Wang  1 , David K Prince  2 , Shannon W Stephens  3 , Heather Herren  4 , Mohamud Daya  5 , Neal Richmond  6 , Jestin Carlson  7 , Craig Warden  8 , M Riccardo Colella  9 , Ashley Brienza  10 , Tom P Aufderheide  11 , Ahamed H Idris  12 , Robert Schmicker  13 , Susanne May  14 , Graham Nichol  15
Affiliations
Randomized Controlled Trial

Design and implementation of the Resuscitation Outcomes Consortium Pragmatic Airway Resuscitation Trial (PART)

Henry E Wang et al. Resuscitation. 2016 Apr.

Abstract

Airway management is an important component of resuscitation from out-of-hospital cardiac arrest (OHCA). The optimal approach to advanced airway management is unknown. The Pragmatic Airway Resuscitation Trial (PART) will compare the effectiveness of endotracheal intubation (ETI) and Laryngeal Tube (LT) insertion upon 72-h survival in adult OHCA. Encompassing United States Emergency Medical Services agencies affiliated with the Resuscitation Outcomes Consortium (ROC), PART will use a cluster-crossover randomized design. Participating subjects will include adult, non-traumatic OHCA requiring bag-valve-mask ventilation. Trial interventions will include (1) initial airway management with ETI and (2) initial airway management with LT. The primary and secondary trial outcomes are 72-h survival and return of spontaneous circulation. Additional clinical outcomes will include airway management process and adverse events. The trial will enroll a total of 3000 subjects. Results of PART may guide the selection of advanced airway management strategies in OHCA.

Keywords: Airway management; Cardiopulmonary arrest; Clinical trials; Emergency medical services; Intubation (intratracheal); Resuscitation.

PubMed Disclaimer

Conflict of interest statement

CONFLICT OF INTEREST STATEMENT

The authors declare no financial or other conflicts of interest.

Figures

FIGURE 1
FIGURE 1
Resuscitation Outcomes Consortium centers participating in PART.
FIGURE 2
FIGURE 2
Overview of PART protocol. ETI = endotracheal intubation. LT = laryngeal tube. BVM = bag-valve-mask ventilation. EMS = Emergency Medical Services.
See this image and copyright information in PMC

References

    1. Go AS, Mozaffarian D, Roger VL, et al. Heart Disease and Stroke Statistics--2014 Update: A Report From the American Heart Association. Circulation. 2013 - PMC - PubMed
    1. Institute of Medicine. [Accessed October 9, 2015];Strategies to Improve Cardiac Arrest Survival: A Time to Act. 2015 at http://www.nap.edu/read/21723/chapter/1.
    1. DeLeo BC. Endotracheal intubation by rescue squad personnel. Heart Lung. 1977;6:851–854. - PubMed
    1. Guss DA, Posluszny M. Paramedic orotracheal intubation: a feasibility study. Am J Emerg Med. 1984;2:399–401. - PubMed
    1. Jacobs LM, Berrizbeitia LD, Bennett B, Madigan C. Endotracheal intubation in the prehospital phase of emergency medical care. Jama. 1983;250:2175–2177. - PubMed

Publication types

LinkOut - more resources