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Review
. 2016 Jun 19;428(12):2569-2574.
doi: 10.1016/j.jmb.2016.01.028. Epub 2016 Feb 3.

Mediator Architecture and RNA Polymerase II Interaction

Clemens Plaschka  1 , Kayo Nozawa  1 , Patrick Cramer  2
Affiliations
Review

Mediator Architecture and RNA Polymerase II Interaction

Clemens Plaschka et al. J Mol Biol. .

Abstract

Integrated structural biology recently elucidated the architecture of Mediator and its position on RNA polymerase II. Here we summarize these achievements and list open questions on Mediator structure and mechanism.

Keywords: RNA polymerase II; coactivator; gene transcription; multiprotein complex.

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