Time for a randomised clinical trial evaluating breast conserving surgery compared to mastectomy in ipsilateral mutlifocal breast cancer (MFBC)?

Affiliations

¹ Patient-Centred and Clinical Outcomes Research Group, University of Bristol, Learning and Research Building Level 2, Southmead Hospital, Bristol, BS10 5NB, UK.
² Barts Cancer Centre, Queen Mary University of London Old Anatomy Building, Charterhouse Square, London EC1M 6BQ, UK.
³ Centre for Tumour Biology, John Vane Science Building, Barts Cancer Institute, Queen Mary University of London, Queen Mary University of London, EC1M 6BQ, UK.
⁴ Histopathology, Queen Elizabeth Hospital Birmingham and University of Birmingham, Mindelsohn Way, Edgbaston, Birmingham, B15 2WB, UK.
⁵ Nightingale Centre and Genesis Prevention Centre, University Hospital of South Manchester, Southmoor Road, Manchester M23 9LT, UK.
⁶ Surgical and Interventional Trials Unit, Division of Surgery and Interventional Science, 132 Hampstead Road, London University College London, NW1 2BX, UK.
⁷ University California San Francisco Carol Franc Buck Breast Care Center, 1600 Divisadero Box 1710, San Francisco, CA 94115, USA.
⁸ Division of Surgical Oncology and Endocrine Surgery, Department of Surgery, University of Texas Health Science Center, 7703 Floyd Curl Drive, Mail Code 7738, San Antonio, TX 78229-3900, USA.
⁹ Breast Cancer Centre, University Hospitals of North Midlands and Keele University, Stoke on Trent ST4 6QG, UK.

Comment

Z E Winters et al. Breast. 2016 Apr.

. 2016 Apr:26:149-50.

doi: 10.1016/j.breast.2015.12.011. Epub 2016 Feb 3.

¹ Patient-Centred and Clinical Outcomes Research Group, University of Bristol, Learning and Research Building Level 2, Southmead Hospital, Bristol, BS10 5NB, UK.
² Barts Cancer Centre, Queen Mary University of London Old Anatomy Building, Charterhouse Square, London EC1M 6BQ, UK.
³ Centre for Tumour Biology, John Vane Science Building, Barts Cancer Institute, Queen Mary University of London, Queen Mary University of London, EC1M 6BQ, UK.
⁴ Histopathology, Queen Elizabeth Hospital Birmingham and University of Birmingham, Mindelsohn Way, Edgbaston, Birmingham, B15 2WB, UK.
⁵ Nightingale Centre and Genesis Prevention Centre, University Hospital of South Manchester, Southmoor Road, Manchester M23 9LT, UK.
⁶ Surgical and Interventional Trials Unit, Division of Surgery and Interventional Science, 132 Hampstead Road, London University College London, NW1 2BX, UK.
⁷ University California San Francisco Carol Franc Buck Breast Care Center, 1600 Divisadero Box 1710, San Francisco, CA 94115, USA.
⁸ Division of Surgical Oncology and Endocrine Surgery, Department of Surgery, University of Texas Health Science Center, 7703 Floyd Curl Drive, Mail Code 7738, San Antonio, TX 78229-3900, USA.
⁹ Breast Cancer Centre, University Hospitals of North Midlands and Keele University, Stoke on Trent ST4 6QG, UK.

No abstract available

Comment on

Conservative surgery for multifocal/multicentric breast cancer.
Nijenhuis MV, Rutgers EJ. Nijenhuis MV, et al. Breast. 2015 Nov;24 Suppl 2:S96-9. doi: 10.1016/j.breast.2015.07.023. Epub 2015 Aug 21. Breast. 2015. PMID: 26303986

Optimising Breast Conservation Treatment for Multifocal and Multicentric Breast Cancer: A Worthwhile Endeavour?: Reply.
Tan MP, Sitoh NY, Sitoh YY. Tan MP, et al. World J Surg. 2017 Jan;41(1):346-347. doi: 10.1007/s00268-016-3590-2. World J Surg. 2017. PMID: 27272268 No abstract available.
Current practice and provision of oncoplastic breast-conserving surgery in the UK: results of the ANTHEM national practice questionnaire.
Davies C, Whisker L, Skillman J, Macmillan D, Holcombe C, Fairbrother P, Potter S; ANTHEM Study Steering Group. Davies C, et al. Breast Cancer Res Treat. 2023 Jul;200(2):163-170. doi: 10.1007/s10549-023-06924-0. Epub 2023 May 22. Breast Cancer Res Treat. 2023. PMID: 37213038 Free PMC article.