The use of magnetic nanoparticles in cancer theranostics: Toward handheld diagnostic devices

Abstract

Magnetic nanoparticles are frequently used in a wide range of biomedical applications. In the first part of this review the most commonly used preparation and surface coating approaches of MNPs are briefly summarized including multifunctional hybrid particles. The second part gives a detailed overview of the use of MNPs in "traditional" biomedical applications related to cancer theranostics, like magnetic resonance imaging, drug delivery, hyperthermia and also their applicability in the next generation of point of care devices based on micro nuclear magnetic resonance and surface enhanced Raman spectroscopic detection technology that all can be routinely applied in everyday clinical practice.

Keywords: Carbon nanomaterial; Hyperthermia; Magnetic nanoparticle; Magnetic resonance imaging; Micro nuclear magnetic resonance; Surface enhanced Raman spectroscopy; Targeted drug delivery.