Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1989 Oct;9(10):4571-5.
doi: 10.1128/mcb.9.10.4571-4575.1989.

Elongation factor EF-1 alpha gene dosage alters translational fidelity in Saccharomyces cerevisiae

J M Song  1 , S Picologlou, C M Grant, M Firoozan, M F Tuite, S Liebman
Affiliations

Elongation factor EF-1 alpha gene dosage alters translational fidelity in Saccharomyces cerevisiae

J M Song et al. Mol Cell Biol. 1989 Oct.

Abstract

Changes in the dosage of genes encoding elongation factor EF-1 alpha were shown to cause parallel changes in the misreading of nonsense codons. Higher amounts of EF-1 alpha were correlated with increased nonsense suppression, suggesting that the level of EF-1 alpha is critically involved in translational fidelity.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Nature. 1970 Aug 15;227(5259):680-5 - PubMed
    1. Genetics. 1988 Dec;120(4):923-34 - PubMed
    1. J Mol Biol. 1975 Nov 5;98(3):503-17 - PubMed
    1. Genetics. 1976 Feb;82(2):251-72 - PubMed
    1. Anal Biochem. 1976 May 7;72:248-54 - PubMed

Publication types

MeSH terms

LinkOut - more resources