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. 2016 Feb 6;7(1):162-70.
doi: 10.4292/wjgpt.v7.i1.162.

Economic evaluations in gastroenterology in Brazil: A systematic review

Luciana Bertocco de Paiva Haddad  1 , Tassia Cristina Decimoni  1 , Jose Antonio Turri  1 , Roseli Leandro  1 , Patrícia Coelho de Soárez  1
Affiliations

Economic evaluations in gastroenterology in Brazil: A systematic review

Luciana Bertocco de Paiva Haddad et al. World J Gastrointest Pharmacol Ther. .

Abstract

Aim: To systematically review economic evaluations in gastroenterology, relating to Brazil, published between 1980 and 2013.

Methods: We selected full and partial economic evaluations from among those retrieved by searching the following databases: MEDLINE (PubMed); Excerpta Medica; the Latin American and Caribbean Health Sciences Literature database; the Scientific Electronic Library Online; the database of the Centre for Reviews and Dissemination; the National Health Service (NHS) Economic Evaluation Database; the NHS Health Technology Assessment database; the Health Economics database of the Brazilian Virtual Library of Health; Scopus; Web of Science; and the Brazilian Network for the Evaluation of Health Technologies. Two researchers, working independently, selected the studies and extracted the data.

Results: We identified 535 health economic evaluations relating to Brazil and published in the 1980-2013 period. Of those 535 articles, only 40 dealt with gastroenterology. Full and partial economic evaluations respectively accounted for 23 (57.5%) and 17 (42.5%) of the 40 studies included. Among the 23 full economic evaluations, there were 11 cost-utility analyses, seven cost-effectiveness analyses, four cost-consequence analyses, and one cost-minimization analysis. Of the 40 studies, 25 (62.5%) evaluated medications; 7 (17.5%) evaluated procedures; and 3 (7.5%) evaluated equipment. Most (55%) of the studies were related to viral hepatitis, and most (63.4%) were published after 2010. Other topics included gastrointestinal cancer, liver transplantation, digestive diseases and hernias. Over the 33-year period examined, the number of such economic evaluations relating to Brazil, especially of those evaluating medications for the treatment of hepatitis, increased considerably.

Conclusion: Further studies are needed in order to ensure that expenditures on health care in Brazil are made as fairly and efficiently as possible.

Keywords: Brazil; Cost-benefit analysis; Costs and cost analysis; Gastroenterology; Health care costs.

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Figures

Figure 1
Figure 1
Flow diagram of the process for the selection of economic evaluations in gastroenterology related to Brazil, 1980-2013. EMBASE: Excerpta Medica; LILACS: Latin American and Caribbean Health Sciences Literature; SciELO: Scientific Electronic Library Online; NHS EED: (United Kingdom) National Health Service Economic Evaluation Database; HTA: Health Technology Assessment; BVS ECOS: Biblioteca Virtual em Saúde Economia da Saúde [Health Economics (database) of the (Brazilian) Virtual Library of Health]; Bireme: Biblioteca Regional de Medicina (Regional Library of Medicine); JBES: Jornal Brasileiro de Economia da Saúde (Brazilian Journal of Health Economics); SISREBRATS: Sistema de Informação da Rede Brasileira de Avaliação de Tecnologias em Saúde (Brazilian Network for the Evaluation of Health Technologies); EES: Economic evaluation study.
Figure 2
Figure 2
Number of economic evaluations in gastroenterology related to Brazil, by type, 1982-2013. CUA: Cost-utility analysis; CCA: Cost-consequence analysis; CEA: Cost-effectiveness analysis; CMA: Cost-minimization analysis; CD: Cost description; CA: Cost analysis; COD: Cost-outcome description.
Figure 3
Figure 3
Number and proportional distribution of economic evaluations in gastroenterology related to Brazil, by publication date and theme, 1982-2013.
Figure 4
Figure 4
Means and standard deviations for Journal Citation Report impact factors among economic evaluations in gastroenterology related to Brazil, by year of publication, 2000-2013.
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