The guanosine binding site of the Tetrahymena ribozyme
- PMID: 2685606
- DOI: 10.1038/342391a0
The guanosine binding site of the Tetrahymena ribozyme
Abstract
The self-splicing Group I introns have a highly specific binding site for the substrate guanosine. Mutant versions of the Tetrahymena ribozyme have been used in combination with guanosine analogues to identify the nucleotide in the ribozyme that is primarily responsible for recognition of the guanine base.
Comment in
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Genetic code origins.Nature. 1989 Nov 23;342(6248):349-50. doi: 10.1038/342349b0. Nature. 1989. PMID: 2479837 No abstract available.
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