Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 2016 May;38(5):751-9.
doi: 10.1007/s10529-016-2050-2. Epub 2016 Feb 8.

Comparison of adult stem cells derived from multiple stem cell niches

Dong-Hun Woo  1 , Hyung Seo Hwang  2 , Joong Hyun Shim  3
Affiliations
Comparative Study

Comparison of adult stem cells derived from multiple stem cell niches

Dong-Hun Woo et al. Biotechnol Lett. 2016 May.

Abstract

Objectives: Adult stem cells (ASCs) have great potential for tissue regeneration; however, comparative studies of ASCs from different niches are required to understand the characteristics of each population for their potential therapeutic uses.

Results: We compared the proliferation, stem cell marker expression, and differentiation potential of ASCs from bone marrow, skin dermis, and adipose tissue. ASCs from bone marrow and skin dermis showed 50-100 % increased proliferation in comparison to the ASCs from adipose tissues. Furthermore, ASCs from each stem cell niche showed differential expression of stem cell marker genes, and preferentially differentiated into cell types of their tissue of origin.

Conclusion: Different characters of each ASC might be major factors for their effective use for therapeutics and tissue regeneration.

Keywords: Adipose derived stem cells; Adult stem cells; Human dermal stem/progenitor cells; Mesenchymal stem cell; Multipotency.

PubMed Disclaimer

Publication types

LinkOut - more resources