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Case Reports
. 2016 May 17;188(8):604.
doi: 10.1503/cmaj.150393. Epub 2016 Feb 8.

Blue man syndrome

Umjeet Jolly  1 , George Klein  2
Affiliations
Case Reports

Blue man syndrome

Umjeet Jolly et al. CMAJ. .
No abstract available

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Figures

Figure 1:
Figure 1:
(A) Photograph of a 73-year-old man presenting with a bluish-grey skin discolouration, predominantly in sun-exposed areas. (B) Near-complete resolution of the discolouration was seen one year after amiodarone was stopped.
See this image and copyright information in PMC

References

    1. Enseleit F, Wyss CA, Duru F, et al. Images in cardiovascular medicine. The blue man: amiodarone-induced skin discoloration. Circulation 2006;113:e63. - PubMed
    1. Delage C, Lagace R, Huard J. Pseudocyanotic pigmentation of the skin induced by amiodarone: a light and electron microscopic study. Can Med Assoc J 1975;112:1205–8. - PMC - PubMed
    1. Alinovi A, Reverberi C, Melissari M, et al. Cutaneous hyperpigmentation induced by amiodarone hydrochloride. J Am Acad Dermatol 1985;12:563–6. - PubMed
    1. Ammoury A, Michaud S, Paul C, et al. Photodistribution of blue–gray hyperpigmentation after amiodarone treatment: Molecular characterization of amiodarone in the skin. Arch Dermatol 2008;144:92–6. - PubMed
    1. Kounis NG, Frangides C, Papadaki PJ, et al. Dose-dependent appearance and disappearance of amiodarone-induced skin pigmentation. Clin Cardiol 1996;19:592–4. - PubMed

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