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Case Reports
. 2016 Mar;8(3):257-9.
doi: 10.14740/jocmr2458w. Epub 2016 Jan 26.

An Avid Imitator

Dimitrios Farmakiotis  1 , Alexis Liakos  2 , Michael B Miller  3 , Jeffrey F Krane  3 , Lindsey R Baden  2 , Sarah P Hammond  2
Affiliations
Case Reports

An Avid Imitator

Dimitrios Farmakiotis et al. J Clin Med Res. 2016 Mar.

Abstract

We present a case of disseminated cryptococcal disease, coexisting with and mimicking lymphoma. Determination of serum cryptococcal antigen should be considered for lymphopenic patients with hematologic malignancies, presenting with unexplained fever, and/or lymphadenopathy and/or pulmonary findings. Patients with hematologic malignancies treated with chemotherapy regimens are susceptible to diverse opportunistic infections. Therefore, in this patient population, it is often necessary to obtain a definitive pathologic diagnosis, to diagnose uncommon syndromes and guide management.

Keywords: Cryptococcus; Lymphoma; Opportunistic infections.

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Figures

Figure 1
Figure 1
(A) PET/CT showing enlarged, FDG-avid mediastinal lymphadenopathy. (B) Hematoxylin-eosin and (C) mucicarmine stains of an endobronchial ultrasound-guided fine-needle aspirate from the mediastinal lymph node showing many encapsulated yeast forms with narrow-based budding, morphologically consistent with Cryptococcus species.
See this image and copyright information in PMC

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