Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2016 Feb 10;8(3):165-72.
doi: 10.4253/wjge.v8.i3.165.

Treatment of gastric outlet obstruction that results from unresectable gastric cancer: Current evidence

Yasuhiro Miyazaki  1 , Shuji Takiguchi  1 , Tsuyoshi Takahashi  1 , Yukinori Kurokawa  1 , Tomoki Makino  1 , Makoto Yamasaki  1 , Kiyokazu Nakajima  1 , Masaki Mori  1 , Yuichiro Doki  1
Affiliations
Review

Treatment of gastric outlet obstruction that results from unresectable gastric cancer: Current evidence

Yasuhiro Miyazaki et al. World J Gastrointest Endosc. .

Abstract

Malignant gastric outlet obstruction (GOO) is a common condition that results from locally advanced malignancies in the upper gastrointestinal tract, such as pancreatic, gastric, and other carcinomas. Two types of procedures for malignant GOO, namely, gastrojejunostomy (GJ) with laparotomy or a laparoscopic approach and endoscopic stenting (ES), are currently available. Although numerous previous reports have clarified the benefits and drawbacks of each procedure, whether GJ or ES should be used in patients with GOO that results from gastric cancer who may have a longer life expectancy than patients with other malignancies has not been determined. In this review, which focuses on gastric cancer-induced GOO, we analyzed the two systematic reviews and a meta-analysis that compared GJ and ES and outlined the current status of GOO treatment. We also provide an updated review that includes laparoscopic GJ. Various data from 13 studies in one review and 6 studies in another review were analyzed. Although the main results of the present review indicated that both GJ and ES were efficacious treatments in patients with GOO that resulted from gastric cancer, current evidence suggests that GJ may be the preferable procedure given its good performance status and improved prognosis in gastric cancer patients.

Keywords: Endoscopic stenting; Gastric cancer; Gastric outlet obstruction; Gastrojejunostomy; Review.

PubMed Disclaimer

References

    1. Del Piano M, Ballarè M, Montino F, Todesco A, Orsello M, Magnani C, Garello E. Endoscopy or surgery for malignant GI outlet obstruction? Gastrointest Endosc. 2005;61:421–426. - PubMed
    1. Pinto Pabón IT, Díaz LP, Ruiz De Adana JC, López Herrero J. Gastric and duodenal stents: follow-up and complications. Cardiovasc Intervent Radiol. 2001;24:147–153. - PubMed
    1. Park KB, Do YS, Kang WK, Choo SW, Han YH, Suh SW, Lee SJ, Park KS, Choo IW. Malignant obstruction of gastric outlet and duodenum: palliation with flexible covered metallic stents. Radiology. 2001;219:679–683. - PubMed
    1. Lopera JE, Brazzini A, Gonzales A, Castaneda-Zuniga WR. Gastroduodenal stent placement: current status. Radiographics. 2004;24:1561–1573. - PubMed
    1. Jeurnink SM, van Eijck CH, Steyerberg EW, Kuipers EJ, Siersema PD. Stent versus gastrojejunostomy for the palliation of gastric outlet obstruction: a systematic review. BMC Gastroenterol. 2007;7:18. - PMC - PubMed

LinkOut - more resources