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. 1977 Jul;74(7):3038-42.
doi: 10.1073/pnas.74.7.3038.

Fatty liver induced in Zucker "fatty" (ff) rats by a semisynthetic diet rich in sucrose

P M Novikoff

Fatty liver induced in Zucker "fatty" (ff) rats by a semisynthetic diet rich in sucrose

P M Novikoff. Proc Natl Acad Sci U S A. 1977 Jul.

Abstract

A new fatty liver model is described in which heredity plays a major role. A marked fatty liver develops when the homozygous mutant Zucker rat (ff or "fatty") is fed a semisynthetic diet enriched in sucrose. Lean littermates do not develop fatty liver on this experimental diet. Even old ff rats do not develop fatty livers on chow; the experimental diet is required. The fatty liver is described, including light microscopic and preliminary electron microscopic observations.

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References

    1. Proc Natl Acad Sci U S A. 1960 Feb;46(2):178-86 - PubMed
    1. Proc Soc Exp Biol Med. 1955 Oct;90(1):270-1 - PubMed
    1. Endocrinology. 1963 May;72:709-14 - PubMed
    1. Gastroenterology. 1958 Apr;34(4):686-93 - PubMed
    1. Am J Pathol. 1952 May-Jun;28(3):387-99 - PubMed

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