doi: 10.1128/AAC.33.10.1822.
Evaluation of cilofungin (LY121019) for treatment of experimental Candida albicans endocarditis in rabbits
Affiliations
- PMID: 2686548
- PMCID: PMC172764
- DOI: 10.1128/AAC.33.10.1822
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Evaluation of cilofungin (LY121019) for treatment of experimental Candida albicans endocarditis in rabbits
Antimicrob Agents Chemother.
1989 Oct.
Abstract
The efficacy of cilofungin (LY121019) for aortic valve endocarditis caused by Candida albicans in rabbits was studied. Vegetation titers were similar for cilofungin-treated and untreated rabbits. No rabbit survived beyond 5 days in either group. All rabbits given amphotericin B survived, and titers were reduced. Cilofungin was ineffective in this model.
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