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doi: 10.1016/j.chom.2016.01.014.
Alcohol Lowers Your (Intestinal) Inhibitions
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- PMID: 26867168
- DOI: 10.1016/j.chom.2016.01.014
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Alcohol Lowers Your (Intestinal) Inhibitions
Cell Host Microbe.
.
Free article
Abstract
Alcohol causes microbiota dysbiosis and breaches intestinal integrity, resulting in liver inflammation and ultimately cirrhosis. In this issue of Cell Host & Microbe, Wang et al. (2016) demonstrate that ethanol suppresses the intestinal anti-microbial response. This enables gut bacteria to trespass to the liver and thus exacerbates the disease progression.
Copyright © 2016 Elsevier Inc. All rights reserved.
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Intestinal REG3 Lectins Protect against Alcoholic Steatohepatitis by Reducing Mucosa-Associated Microbiota and Preventing Bacterial Translocation.Cell Host Microbe. 2016 Feb 10;19(2):227-39. doi: 10.1016/j.chom.2016.01.003. Cell Host Microbe. 2016. PMID: 26867181 Free PMC article.
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