CRISPR-Cas Gatekeeper: Slow on the Uptake but Gets the Job Done
- PMID: 26867170
- DOI: 10.1016/j.chom.2016.01.015
CRISPR-Cas Gatekeeper: Slow on the Uptake but Gets the Job Done
Abstract
Microbial CRISPR-Cas acts as a defense, but also as a gatekeeper controlling the flow of new genes into microbial genomes. In a recent Cell paper, Jiang et al. (2016) uncover the functional importance of transcription-dependent RNA targeting in type III-A CRISPR-Cas antiviral defense and provide insight into the co-evolution of virus-host symbioses.
Copyright © 2016 Elsevier Inc. All rights reserved.
Comment on
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Degradation of Phage Transcripts by CRISPR-Associated RNases Enables Type III CRISPR-Cas Immunity.Cell. 2016 Feb 11;164(4):710-21. doi: 10.1016/j.cell.2015.12.053. Epub 2016 Feb 4. Cell. 2016. PMID: 26853474 Free PMC article.
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