Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016;20S(Suppl):12-5.
doi: 10.1016/j.ijscr.2016.02.003. Epub 2016 Feb 3.

Primary angiosarcoma of the breast

Daniele Bordoni  1 , Elisa Bolletta  2 , Giuseppe Falco  3 , Pierfrancesco Cadenelli  4 , Nicola Rocco  5 , Ariel Tessone  6 , Stefania Guarino  7 , Antonello Accurso  8 , Bruno Amato  9 , Cesare Magalotti  1
Affiliations

Primary angiosarcoma of the breast

Daniele Bordoni et al. Int J Surg Case Rep. 2016.

Abstract

Primary angiosarcoma (AS) of the breast is a rare neoplasia that is not related to radiation exposure. It represents less than 0.05% of all malignant breast tumors. This lesion is characterized by aggressive patterns and poor prognosis and by the absence of typical features at radiologic examination. Currently there are not evidence-based guidelines regarding surgical and adjuvant treatment for this tumor even though wide surgical resection followed by chemo- radiotherapy appears to improve both disease free survival and overall survival. The aim of this study was to analyze the available series of AS patients suggesting the most reliable treatment options for this rare neoplasia.

Keywords: Angiosarcoma; Breast cancer; Breast sarcomas.

PubMed Disclaimer

References

    1. Adem C., Reynolds C., Ingle J.N., Nascimento A.G. Primary breast sarcoma: clinicopathologic series from the Mayo Clinic and review of the literature. Br. J. Cancer. 2004;91:237–241. - PMC - PubMed
    1. Liberman L., Dershaw D.D., Kaufman R.J., Rosen P.P. Angiosarcoma of the breast. Radiology. 1992;183:e649–e654. - PubMed
    1. Lagrange J.L., Ramaioli A., Chateau M.C. Sarcoma after radiation therapy. Radiology. 2000;216:197–205. - PubMed
    1. Blanchard D.K., Reynolds C., Grant C.S., Farley D.R., Donohue J.H. Radiation-induced breast sarcoma. Am. J. Surg. 2002;184:356–358. - PubMed
    1. Huang J., Mackillop W.J. Increased risk of soft tissue sarcoma after radiotherapy in women with breast carcinoma. Cancer. 2001;92:172–180. - PubMed