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. 2015 Nov-Dec;31(6):1437-40.
doi: 10.12669/pjms.316.8247.

The predictive factors for lymph node metastasis in early gastric cancer: A clinical study

Yinzhong Wang  1
Affiliations

The predictive factors for lymph node metastasis in early gastric cancer: A clinical study

Yinzhong Wang. Pak J Med Sci. 2015 Nov-Dec.

Abstract

Objective: To detect the clinicopathological factors associated with lymph node metastases in early gastric cancer.

Methods: We retrospectively evaluated the distribution of metastatic nodes in 198 patients with early gastric cancer treated in our hospital between May 2008 and January 2015, the clinicopathological factors including age, gender, tumor location, tumor size, macroscopic type, depth of invasion, histological type and venous invasion were studied, and the relationship between various parameters and lymph node metastases was analyzed.

Results: In this study, one hundred and ninety-eight patients with early gastric cancer were included, and lymph node metastasis was detected in 28 patients. Univariate analysis revealed a close relationship between tumor size, depth of invasion, histological type, venous invasion, local ulceration and lymph node metastases. Multivariate analysis revealed that the five factors were independent risk factors for lymph node metastases.

Conclusion: The clinicopathological parameters including tumor size, depth of invasion, local ulceration, histological type and venous invasion are closely correlated with lymph node metastases, should be paid high attention in early gastric cancer patients.

Keywords: Depth of invasion; Early gastric cancer (EGC); Histological type; Local ulceration; Lymph node metastases; Tumor size; Venous invasion.

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References

    1. Ma M, Chen S, Zhu BY, Zhao BW, Wang HS, Xiang J, et al. The clinical significance and risk factors of solitary lymph node metastasis in gastric cancer. PLoS One. 2015;10(1):e0114939. doi: 10.1371/journal.pone.0114939. - PMC - PubMed
    1. Ren G, Cai R, Zhang WJ, Ou JM, Jin YN, Li WH. Prediction of risk factors for lymph node metastasis in early gastric cancer. World J Gastroenterol. 2013;19(20):3096–3107. doi: 10.3748/wjg.v19.i20.3096. - PMC - PubMed
    1. Hacibekiroglu I, Kodaz H, Erdogan B, Turkmen E, Esenkaya A, Uzunoglu S, et al. Comparative Analysis of the Efficacy and Safety of Oxaliplatin Plus 5-Fluorouracil/Leucovorin (Modified FOLFOX6) with Advanced Gastric Cancer Patients having a Good or Poor Performance Status. Asian Pac J Cancer Prev. 2015;16(6):2355–2359. - PubMed
    1. Liu CG, Lu P, Lu Y, Jin F, Xu HM, Wang SB, et al. Distribution of solitary lymph nodes in primary gastric cancer: a retrospective study and clinical implications. World J Gastroenterol. 2007;13(35):4776–4780. - PMC - PubMed
    1. Hirasawa T, Gotoda T, Miyata S, Kato Y, Shimoda T, Taniguchi H, et al. Incidence of lymph node metastasis and the feasibility of endoscopic resection for undifferentiated-type early gastric cancer. Gastric Cancer. 2009;12(3):148–152. doi: 10.1007/s10120-009-0515-x. - PubMed

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