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Case Reports
. 2015 Nov-Dec;31(6):1545-8.
doi: 10.12669/pjms.316.8391.

Pulmonary renal syndrome in a patient with vasculitis: Case report and review of literature

Aijaz Zeeshan Khan Chachar  1 , Omer Sabir  2 , Irfan Haider  3 , Imrana Tanvir  4 , Kashif Rafique  5 , Nauman Tarif  6
Affiliations
Case Reports

Pulmonary renal syndrome in a patient with vasculitis: Case report and review of literature

Aijaz Zeeshan Khan Chachar et al. Pak J Med Sci. 2015 Nov-Dec.

Abstract

Granulomatosis with polyangiitis (GPA) previously known as Wegner's granulomatosis, is a small vessel vasculitis that preferentially involves capillaries, arterioles and venules, presenting as multisystemic disease classically with alveolar haemorrhage and renal insufficiency. We report a case of GPA diagnosed on history, clinical findings and supported by imaging and very high levels of C-ANCA. Renal biopsy confirmed the typical histopathological findings. We discuss herein the management of the case and review of literature.

Keywords: Cyclophoshamide; Granulomatosis with polyangiitis; Plasmapheresis; Small vessel vasculitis.

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Figures

Fig.1
Fig.1
A) Chest x-ray revealed lower zones infiltrates more on right side (shown by arrows). (B) Patchy shadowing in lower zones (as shown by arrows) on high resolution computer tomography (HRCT), indicating alveolar hemorrhage. (C) Remarkable improvement noted on HRCT, showing disappearance of Hemorrhage as shown by arrows as compared to Fig.1-B.
Fig.2
Fig.2
Renal biopsy slide showing Crescenteric pattern (shown by arrows).
See this image and copyright information in PMC

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