Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016 Jan;11(1):283-286.
doi: 10.3892/ol.2015.3911. Epub 2015 Nov 12.

Giant recurrent dumbbell-shaped hypoglossal schwannoma in an elderly male: A case report

Zhiyun Yu  1 , Gang Zhao  1 , Zhongying Zhao  2 , Yunqian Li  1 , Guifang Xie  3
Affiliations

Giant recurrent dumbbell-shaped hypoglossal schwannoma in an elderly male: A case report

Zhiyun Yu et al. Oncol Lett. 2016 Jan.

Abstract

Dumbbell-shaped hypoglossal Schwannomas of the 12th cranial nerve are extremely rare, and complete removal of these tumors is difficult, particularly in elderly patients with recurrent tumors. The present study reports the case of a 61-year-old male with a giant recurrent dumbbell-shaped hypoglossal schwannoma that arose extracranially. The recurrent tumor was completely removed in a one-stage surgical procedure via the far lateral suboccipital approach in combination with the transcervical approach. To the best of our knowledge, such a lesion has not been reported previously. The life expectancy and natural course of the disease are important factors to take into account when considering the individual end-point of surgery in patients. More studies on hypoglossal schwannomas are required, particularly cases in which the hypoglossal schwannoma was not totally resected, not only in order to develop more definitive and secure surgical treatments, but also to reduce the resultant unnecessary suffering of patients.

Keywords: dumbbell-shaped; elderly; far lateral approach; hypoglossal schwannoma; recurrent.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
High-resolution computed tomography scans showing (A) a mass located in the left parapharyngeal space, and (B) with no tumor in the cerebellopontine angle.
Figure 2.
Figure 2.
Dumbbell-shaped tumor located in (A) the left parapharyngeal space and (B) the left cerebellopontine angle. (C) The tumor showed inhomogeneous signal intensity on T2-weighted magnetic resonance imaging.
Figure 3.
Figure 3.
Initial extracranial tumor: Photomicrograph showing spindle-shaped tumor cells stained with Hematoxylin and eosin at (A) ×20 and (B) ×40 magnification. For recurrent dumbbell-shaped tumor: Histological appearance of the lesion at (C) ×20 and (D) ×40 magnification showing the showing typical spindle-shaped tumor cells, with nuclear palisading and relatively thin-walled vessels. Mitotic figures were increased and nuclear atypia was limited.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. De Martel T, Subirana A, Guillaume J. Los tumores de le fosa cerebral posterior: Voluminoso neurinoma del hipogloso con desarrollo juxtabulbo-protuberancial. Operacioncuracion Ars Med. 1933;9:416–419.
    1. Baghel PS, Gupta A, Tripathi VD, Reddy DS. Hypoglossal schwannoma presenting as hemi-atrophy of the tongue. Neurol India. 2013;61:324–325. doi: 10.4103/0028-3886.115092. - DOI - PubMed
    1. Hoshi M, Yoshida K, Ogawa K, Kawase T. Hypoglossal neurinoma-two case reports. Neurol Med Chir (Tokyo) 2000;40:489–493. doi: 10.2176/nmc.40.489. - DOI - PubMed
    1. Jia G, Wang Z, Zhang J. Diagnosis and treatment of hypoglossal neurinoma. Zhonghua Yi Xue Za Zhi. 2001;81:1264–1265. (In Chinese) - PubMed
    1. Li WC, Hong XY, Wang LP, Ge PF, Fu SL, Luo YN. Large cystic hypoglossal schwannoma with fluid-fluid level: A case report. Skull Base. 2010;20:193–197. doi: 10.1055/s-0029-1246219. - DOI - PMC - PubMed

LinkOut - more resources