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Comparative Study
. 1989 Dec;27(12):2880.
doi: 10.1128/jcm.27.12.2880-.1989.

Evaluation of five hepatitis delta virus marker assays for detection of antigen and antibody

A Bezeaud  1 , M Rosenswajg, M C Guillin
Affiliations
Comparative Study

Evaluation of five hepatitis delta virus marker assays for detection of antigen and antibody

A Bezeaud et al. J Clin Microbiol. 1989 Dec.

Abstract

Five commercially available assays for hepatitis delta (HD) virus markers were compared for sensitivity, specificity, and reproducibility: three assays for antibody (anti-HD), provided by Diagnostics Pasteur, Organon Teknika, and Abbott Laboratories, and two assays for antigen (HD Ag), from Pasteur and Organon Teknika. The assay from Organon Teknika is the less sensitive assay for anti-HD detection. Although the sensitivities of the Pasteur and Abbott assays for anti-HD detection are similar, the use of Abbott reagents is hampered by the lack of specificity when HD Ag is present. The greater sensitivity for HD Ag detection is obtained with Organon assay.

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References

    1. J Clin Microbiol. 1989 Feb;27(2):373-4 - PubMed
    1. J Clin Microbiol. 1988 Jul;26(7):1339-42 - PubMed

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