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. 1989 Dec;4(12):1509-11.

High levels of the c-myc protein in cell lines of Bloom's syndrome origin

N F Sullivan  1 , A E Willis, J P Moore, T Lindahl
Affiliations
  • PMID: 2687770

High levels of the c-myc protein in cell lines of Bloom's syndrome origin

N F Sullivan et al. Oncogene. 1989 Dec.

Abstract

Lymphoblastoid cell lines derived from cancer prone Bloom's Syndrome patients differ from cell lines representative of several other disorders by exhibiting a constitutive elevation in the level of the c-myc protein. This may be a contributing factor in the strong predisposition to malignancy observed in Bloom's syndrome.

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