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. 2016 Mar;49(2):202-6.
doi: 10.5946/ce.2015.059. Epub 2016 Feb 16.

Tracheal Involvement in Crohn Disease: the First Case in Korea

Seunghyun Park  1 , Jongha Park  1 , Hyun-Kuk Kim  2 , Ji Yeon Kim  3 , So Chong Hur  1 , Ju Hyung Lee  1 , Jae Won Jung  1 , Juwon Lee  1
Affiliations

Tracheal Involvement in Crohn Disease: the First Case in Korea

Seunghyun Park et al. Clin Endosc. 2016 Mar.

Erratum in

Abstract

Respiratory involvement in Crohn disease (CD) is rare condition with only about a dozen reported cases. We report the first case of CD with tracheal involvement in Korea. An 18-year-old woman with CD was hospitalized because of coughing, dyspnea, and fever sustained for 3 weeks. Because she had stridor in her neck, we performed computed tomography of the neck, which showed circumferential wall thickening of the larynx and hypopharynx. Bronchoscopy revealed mucosal irregularity, ulceration, and exudates debris in the proximal trachea, and bronchial biopsy revealed chronic inflammation with granulation tissue. Based on these findings, we suspected CD with tracheal involvement and began administering intravenous methylprednisolone at 1 mg/kg per day, after which her symptoms and bronchoscopic findings improved.

Keywords: Crohn disease; Inflammatory bowel diseases; Tracheobronchial involvement.

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Conflict of interest statement

Conflicts of Interest: The authors have no financial conflicts of interest.

Figures

Fig. 1.
Fig. 1.
(A, B) Computed tomography of neck showed abrupt narrowing of proximal trachea (arrows).
Fig. 2.
Fig. 2.
Flexible bronchoscopy showed mucosal irregularity, edema, and yellowish patch-like mucosal lesion on the proximal part of trachea.
Fig. 3.
Fig. 3.
Bronchoscopic biopsy. (A) Dense inflammatory cell infiltration in the mucosa and submucosa of trachea (H&E stain, ×10). (B) Granulation tissue representing healing of damaged tissue (H&E stain, ×100).
Fig. 4.
Fig. 4.
Flexible bronchoscopy findings after treatment show marked improvement.
See this image and copyright information in PMC

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