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Review
. 2016 Mar;43(1):59-68.
doi: 10.1016/j.ogc.2015.10.002.

Overactive Bladder

Nicola White  1 , Cheryl B Iglesia  2
Affiliations
Review

Overactive Bladder

Nicola White et al. Obstet Gynecol Clin North Am. 2016 Mar.

Abstract

Overactive bladder (OAB) is a condition affecting millions of individuals in the United States. Anticholinergics are the mainstay of treatment. Bladder botulinum toxin injections have shown an improvement in symptoms of OAB equivalent to anticholinergic therapy. Percutaneous tibial nerve stimulation can decrease symptoms of urinary frequency and urge incontinence. Sacral neuromodulation for refractory patients has been approved by the Food and Drug Administration for treatment of OAB, urge incontinence, and urinary retention. Few randomized, head-to-head comparisons of the different available alternatives exist; however, patients now have increasing options to manage their symptoms and improve their quality of life.

Keywords: Anticholinergics; Bladder botulinum toxin (Botox) injection; Overactive bladder; Sacral neuromodulation; Urinary incontinence.

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