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. 2016:2016:5748264.
doi: 10.1155/2016/5748264. Epub 2016 Jan 6.

Hospital Admission Patterns in Children with CAH: Admission Rates and Adrenal Crises Decline with Age

R Louise Rushworth  1 , Henrik Falhammar  2 , Craig F Munns  3 , Ann M Maguire  4 , David J Torpy  5
Affiliations

Hospital Admission Patterns in Children with CAH: Admission Rates and Adrenal Crises Decline with Age

R Louise Rushworth et al. Int J Endocrinol. 2016.

Abstract

Objective. To examine patterns of hospitalisation for acute medical conditions in children with congenital adrenal hyperplasia (CAH). Design. A retrospective study of hospitalisation using administrative data. Setting. All hospitals in NSW, Australia. Patients. All patients admitted with CAH and a random sample of admissions in patients aged 0 to 18 years without adrenal insufficiency (AI). Main Outcome Measures. Admissions and comorbidities by age and sex. Results. Of 573 admissions for medical problems in CAH children, 286 (49.9%) were in males, and 236 (41.2%) had a principal diagnosis of CAH or had an adrenal crisis (AC). 37 (6.5%) ACs were recorded. An infection was found in 43.5% (n = 249) of the CAH patient admissions and 51.7% (n = 1613) of the non-AI group, p < 0.001. Children aged up to one year had the highest number of admissions (n = 149) and six ACs (four in males). There were 21 ACs recorded for children aged 1-5 years. Older CAH children had fewer admissions and fewer ACs. No in-hospital deaths were recorded. Conclusions. Admission for medical problems in CAH children declines with age. An AC was recorded in 6.5% of the admissions, with the majority of ACs occurring in the 1 to 5 years age group and there were no deaths.

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Figures

Figure 1
Figure 1
Total admissions, admissions for principal diagnosis of CAH, and admissions with an adrenal crisis in patients with CAH, NSW, 2000–2013.
See this image and copyright information in PMC

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