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Comment
. 2016 Feb 16;44(2):207-8.
doi: 10.1016/j.immuni.2016.01.026.

Strength in Numbers: Visualizing CTL-Mediated Killing In Vivo

Jeffrey C Nolz  1 , Ann B Hill  2
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Strength in Numbers: Visualizing CTL-Mediated Killing In Vivo

Jeffrey C Nolz et al. Immunity. .
Free article

Abstract

Cytotoxic CD8+ T lymphocytes (CTLs) have long been believed to be extremely efficient killers. Forster and colleagues (Halle et al., 2016) used in vivo imaging to tell a different story, in which each CTL killed only 2-16 targets a day, and several CTLs per target were needed to get the job done.

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