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doi: 10.1016/j.immuni.2016.02.003.
TLRs of Our Fathers
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- PMID: 26885854
- DOI: 10.1016/j.immuni.2016.02.003
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TLRs of Our Fathers
Immunity.
.
Free article
Abstract
Two new studies published in The American Journal of Human Genetics (Dannemann et al., 2016; Deschamps et al., 2016) show that introgression of innate immune genes from Neandertals and Denisovans contributed to the modern genome of European and Asian, but not African, populations, and this might partly explain differences in susceptibility to immune-mediated diseases.
Copyright © 2016 Elsevier Inc. All rights reserved.
Comment on
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Genomic Signatures of Selective Pressures and Introgression from Archaic Hominins at Human Innate Immunity Genes.Am J Hum Genet. 2016 Jan 7;98(1):5-21. doi: 10.1016/j.ajhg.2015.11.014. Am J Hum Genet. 2016. PMID: 26748513 Free PMC article.
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Introgression of Neandertal- and Denisovan-like Haplotypes Contributes to Adaptive Variation in Human Toll-like Receptors.Am J Hum Genet. 2016 Jan 7;98(1):22-33. doi: 10.1016/j.ajhg.2015.11.015. Am J Hum Genet. 2016. PMID: 26748514 Free PMC article.
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