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Review
. 2016 Apr;54(4):860-7.
doi: 10.1128/JCM.00279-16. Epub 2016 Feb 17.

Zika Virus: Diagnostics for an Emerging Pandemic Threat

Jesse J Waggoner  1 , Benjamin A Pinsky  2
Affiliations
Review

Zika Virus: Diagnostics for an Emerging Pandemic Threat

Jesse J Waggoner et al. J Clin Microbiol. 2016 Apr.

Abstract

Zika virus (ZIKV) is anAedesmosquito-borne flavivirus that emerged in Brazil in 2015 and then rapidly spread throughout the tropical and subtropical Americas. Based on clinical criteria alone, ZIKV cannot be reliably distinguished from infections with other pathogens that cause an undifferentiated systemic febrile illness, including infections with two common arboviruses, dengue virus and chikungunya virus. This minireview details the methods that are available to diagnose ZIKV infection.

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Figures

FIG 1
FIG 1
A geographic history of Zika virus. The virus was discovered in 1947 in the Zika forest of Uganda (A). The 2007 outbreak on the Yap Islands in the Federated States of Micronesia heralded the introduction of Zika virus to Oceania (B). The identification of Zika virus in Camaçari in the State of Bahia, Brazil, in 2015 marked the emergence of Zika virus in continental South America (C). World map obtained from FreeVectorMaps.com (http://freevectormaps.com).
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