Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016 May;54(5):1368-71.
doi: 10.1128/JCM.03302-15. Epub 2016 Feb 17.

Evaluation of the Check-Points Check MDR CT103 and CT103 XL Microarray Kits by Use of Preparatory Rapid Cell Lysis

Affiliations

Evaluation of the Check-Points Check MDR CT103 and CT103 XL Microarray Kits by Use of Preparatory Rapid Cell Lysis

Scott A Cunningham et al. J Clin Microbiol. 2016 May.

Abstract

Using a rapid bacterial lysis method, the Check MDR CT103 and CT103 XL microarrays demonstrated accuracies of 98.1% and 94.2%, respectively, for detection of known resistance genes in 108 multidrug-resistant Gram-negative bacilli. In 45 isolates, 49 previously unrecognized extended-spectrum β-lactamase or plasmid AmpC targets were detected and confirmed by conventional PCR.

PubMed Disclaimer

Similar articles

Cited by

References

    1. Nordmann P, Dortet L, Poirel L. 2012. Carbapenem resistance in Enterobacteriaceae: here is the storm! Trends Mol Med 18:263–272. - PubMed
    1. Schreckenberger PC, Reasius V. 2012. Phenotypic detection of β-lactamase resistance in Gram-negative bacilli: testing and interpretation guide. Loyola University Medical Center, Maywood, IL: http://www.scacm.org/PhenotypicDetectionAntibioticResistance_rev5.pdf.
    1. Vasoo S, Cunningham SA, Kohner PC, Simner PJ, Mandrekar JN, Lolans K, Hayden MK, Patel R. 2013. Comparison of a novel, rapid chromogenic biochemical assay, the Carba NP test, with the modified Hodge test for detection of carbapenemase-producing Gram-negative bacilli. J Clin Microbiol 51:3097–3101. doi:10.1128/JCM.00965-13. - DOI - PMC - PubMed
    1. Clinical and Laboratory Standards Institute. 2016. Performance standards for antimicrobial susceptibility testing; 24th informational supplement. CLSI M100-S26. Clinical and Laboratory Standards Institute, Wayne, PA.
    1. Gazin M, Paasch F, Goossens H, Malhotra-Kumar S. 2012. Current trends in culture-based and molecular detection of extended-spectrum-β-lactamase-harboring and carbapenem-resistant Enterobacteriaceae. J Clin Microbiol 50:1140–1146. doi:10.1128/JCM.06852-11. - DOI - PMC - PubMed

Publication types

MeSH terms

LinkOut - more resources