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. 2016 Apr 11;22(16):5547-50.
doi: 10.1002/chem.201600661. Epub 2016 Mar 4.

Copper-Catalyzed S-C/S-N Bond Interconversions

Jian Wen  1 , Hanchao Cheng  1 , Shunxi Dong  1 , Carsten Bolm  2
Affiliations

Copper-Catalyzed S-C/S-N Bond Interconversions

Jian Wen et al. Chemistry. .

Abstract

Under an atmosphere of dioxygen, copper-catalyzed de-alkylation/amination sequences provide sulfonimidamides from unprotected sulfoximines in moderate to good yields. Mechanistic studies suggest the involvement of radicals in both the C-S bond cleavage and the formation of the new N-S bond.

Keywords: copper; demethylation; oxygen; sulfonimidamides; sulfoximines.

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