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Review
. 2016 Mar;45(1):1-16.
doi: 10.1016/j.ecl.2015.09.001.

Familial Hypercholesterolemia

Victoria Enchia Bouhairie  1 , Anne Carol Goldberg  2
Affiliations
Review

Familial Hypercholesterolemia

Victoria Enchia Bouhairie et al. Endocrinol Metab Clin North Am. 2016 Mar.

Abstract

Familial hypercholesterolemia is a common, inherited disorder of cholesterol metabolism that leads to early cardiovascular morbidity and mortality. It is underdiagnosed and undertreated. Statins, ezetimibe, bile acid sequestrants, niacin, lomitapide, mipomersen, and low-density lipoprotein (LDL) apheresis are treatments that can lower LDL cholesterol levels. Early treatment can lead to substantial reduction of cardiovascular events and death in patients with familial hypercholesterolemia. It is important to increase awareness of this disorder in physicians and patients to reduce the burden of this disorder.

Keywords: Bile acid sequestrants; Ezetimibe; Familial hypercholesterolemia; LDL apheresis; Lomitapide; Mipomersen; Statins.

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Republished from

  • Familial hypercholesterolemia.
    Bouhairie VE, Goldberg AC. Bouhairie VE, et al. Cardiol Clin. 2015 May;33(2):169-79. doi: 10.1016/j.ccl.2015.01.001. Cardiol Clin. 2015. PMID: 25939291 Free PMC article. Review.

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