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Review
. 2016 Mar;45(1):39-54.
doi: 10.1016/j.ecl.2015.09.003.

Lipoprotein Apheresis

Patrick M Moriarty  1 , Linda Hemphill  2
Affiliations
Review

Lipoprotein Apheresis

Patrick M Moriarty et al. Endocrinol Metab Clin North Am. 2016 Mar.

Abstract

Patients with familial hypercholesterolemia (FH) have early development of atherosclerosis and cardiovascular disease (CVD). Lipid level-lowering medications are not always successful in reducing increased low-density lipoprotein C (LDL-C) levels. Lipoprotein apheresis (LA) therapy has proven its clinical benefit in reducing CVD events for patients with FH with hypercholesterolemia. LA reduces LDL-C levels by more than 60% in patients with FH and reduces CVD events. LA also reduces Lp(a) levels and CVD events. LA reduces inflammatory markers and blood viscosity.

Keywords: Atherosclerosis; CVD; Familial hypercholesterolemia; LDL-C; Lipoprotein apheresis; Lp(a).

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Republished from

  • Lipoprotein apheresis.
    Moriarty PM, Hemphill L. Moriarty PM, et al. Cardiol Clin. 2015 May;33(2):197-208. doi: 10.1016/j.ccl.2015.02.002. Cardiol Clin. 2015. PMID: 25939293 Review.

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