Signalling: Putting the brakes on KRAS-G12C nucleotide cycling
- PMID: 26893067
- DOI: 10.1038/nrc.2016.13
Signalling: Putting the brakes on KRAS-G12C nucleotide cycling
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Selective Inhibition of Oncogenic KRAS Output with Small Molecules Targeting the Inactive State.Cancer Discov. 2016 Mar;6(3):316-29. doi: 10.1158/2159-8290.CD-15-1105. Epub 2016 Jan 6. Cancer Discov. 2016. PMID: 26739882
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Allele-specific inhibitors inactivate mutant KRAS G12C by a trapping mechanism.Science. 2016 Feb 5;351(6273):604-8. doi: 10.1126/science.aad6204. Epub 2016 Jan 14. Science. 2016. PMID: 26841430 Free PMC article.
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