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. 2015 Summer;6(3):191-7.
Epub 2015 Sep 15.

Synbiotic enhances immune responses against infectious bronchitis, infectious bursal disease, Newcastle disease and avian influenza in broiler chickens

Alireza Talebi  1 , Amir Amani  2 , Masoud Pourmahmod  2 , Poya Saghaei  2 , Reza Rezaie  2
Affiliations

Synbiotic enhances immune responses against infectious bronchitis, infectious bursal disease, Newcastle disease and avian influenza in broiler chickens

Alireza Talebi et al. Vet Res Forum. 2015 Summer.

Abstract

Increased susceptibility of birds to avian pathogens in intensive husbandry system has emphasized on necessity of improvement of innate and specific immune responses of birds by the fast establishment of a beneficial microflora and immune stimulator factors to guarantee healthy and low-price products. During this study, 192 one-day-old broiler chicks (Ross-380) in four groups with three replicates per group were used to investigate effectiveness of synbiotic Biomin Imbo on immune responses of the chickens following routine vaccination against Newcastle disease (ND), avian influenza (AI), infectious bronchitis (IB) and infectious bursal disease (IBD). The results of this study indicated that supplementation of Biomin Imbo in diet enhanced humoral immune responses significantly in the case of ND, IB, IBD (p = 0.049, p = 0.020, p = 0.036, respectively), but insignificantly in the case of AI (p = 0.160) following vaccination of the chickens against these most common important viral poultry diseases. It was more effective following vaccination with live than killed vaccines. In conclusion, application of synbiotic Biomin Imbo, as a feed-additive adjuvant promotes acquired humoral immune responses of broiler chickens.

Keywords: Avian influenza; Biomin Imbo; Infectious bronchitis; Infectious bursal disease; Newcastle disease.

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Figures

Fig. 1
Fig. 1
Effects of Biomin Imbo on Newcastle disease antibody titer of broiler chickens vaccinated with Clone 30 vaccine. V+ Biomin+ (vaccinated and fed with diet containing Biomin Imbo), V+ Biomin- (vaccinated and fed with diet without Biomin Imbo), V- Biomin- (unvaccinated and fed with diet without Biomin Imbo), V- Biomin+ (unvaccinated and fed with diet containing Biomin Imbo).
Fig. 2
Fig. 2
Effects of Biomin Imbo on avian influenza (AI) antibody titer of broiler chickens vaccinated with AI killed vaccine. V+ Biomin+ (vaccinated and fed with diet containing Biomin Imbo), V+ Biomin- (vaccinated and fed with diet without Biomin Imbo), V- Biomin- (unvaccinated and fed with diet without Biomin Imbo), V- Biomin+ (unvaccinated and fed with diet containing Biomin Imbo).
Fig. 3
Fig. 3
Effects of Biomin Imbo on infectious bronchitis antibody titer of broiler chickens vaccinated with Ma5 vaccine. V+ Biomin+ (vaccinated and fed with diet containing Biomin Imbo), V+ Biomin- (vaccinated and fed with diet without Biomin Imbo), V- Biomin- (unvaccinated and fed with diet without Biomin Imbo), V- Biomin + (unvaccinated and fed with diet containing Biomin Imbo
Fig. 4
Fig. 4
Effects of Biomin Imbo on infectious bursal disease antibody titer of broiler chickens vaccinated with D78 vaccine. V+ Biomin + (vaccinated and fed with diet containing Biomin Imbo), V+ Biomin- (vaccinated and fed with diet without Biomin Imbo), V- Biomin- (unvaccinated and fed with diet without Biomin Imbo), V- Biomin+ (unvaccinated and fed with diet containing Biomin Imbo
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