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Case Reports
. 2016;70(1):31-5.
doi: 10.18926/AMO/54001.

A Long-term Survivor after Congenital Acute Myeloid Leukemia with t(8 ; 16)(p11 ; p13)

Takae Hanada  1 , Kiichiro Kanamitsu, Kosuke Chayama, Takako Miyamura, Yui Kanazawa, Michiko Muraoka, Kana Washio, Masahide Imada, Misao Kageyama, Akihito Takeuchi, Kei Tamai, Megumi Oda, Akira Shimada
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Free article
Case Reports

A Long-term Survivor after Congenital Acute Myeloid Leukemia with t(8 ; 16)(p11 ; p13)

Takae Hanada et al. Acta Med Okayama. 2016.
Free article

Abstract

The treatment of patients with congenital leukemia is difficult and often results in a poor prognosis. We present here the case of a female child with congenital acute myeloid leukemia (AML) with t(8 ; 16) (p11 ; p13) who received chemotherapy and survived for more than 10 years without relapse. A novel MOZ-CBP chimera was found in her diagnostic sample. Although adult AML patients with MOZ-CBP have mainly been reported as having therapy-related AML and showed poor prognoses, the present case supports the idea that AML with MOZ-CBP in the pediatric population might show better prognoses.

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